Coiled-coil domain-containing protein 71 (CCDC71)

About Coiled-coil domain-containing protein 71

Coiled-coil domain-containing protein 71 (CCDC71) is a protein from Homo sapiens identified by UniProt accession Q8IV32, 467 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 71
UniProt accession	Q8IV32
Gene	CCDC71
Organism	Homo sapiens
Length	467 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
fat body mass · score 0.15
body fat percentage · score 0.14
insomnia measurement · score 0.14
Irritability · score 0.13
irritability measurement · score 0.12
age at first birth measurement · score 0.12
unipolar depression · score 0.11
body mass index · score 0.09
body weights and measures · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IV32-F1	alphafold	PREDICTED	52.48	—

Amino-acid sequence (467 residues)

MSVVVQHVEE KAVHSWSRIS TAGKKALEEA LLVFNPMSQD LSATEAQLVA FLQGLRDDGF QPTILRSGDV YGYSSCTANP PSQTKLQARA PNPTATSPPA SAPRTAMRLP AGRATLLPMP LSGRLAKAST PALAKHATTN LLLSSLKQSS ASHARGAAVG FPTHLYPGVY PAMRLSVVLE ALVPLKTPMP CLGAKHKAQS LQLSLADSPL KLRKSSGKGP GNPRPKAPRK TTSKGPKCLT RKGPGAGPRR GSGHQSKTNR ATGSPSVRRM KGGSALGTKT AQAKVARTLA KAARAQAKVA RTQAKAAKAR AKAKAAQVKA KAKAKAAQVK AKAKVMAAWA KAKAKAKAVR AKAKVARTQP RGRGRPKGSA KARTTRKGQK NRPETVGQKR KRAEEAKDLP PKKRTRLGPR SPKAWLGPGT AKLLKFRAIK VDRRSSDDEV RQRAQRILRV NLSPVIRLQP LLPYSAV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards