About Uncharacterized protein KIAA0825
Uncharacterized protein KIAA0825 (KIAA0825) is a protein
from Homo sapiens identified by UniProt accession
Q8IV33, 1275 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Uncharacterized protein KIAA0825 |
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| UniProt accession | Q8IV33 |
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| Gene | KIAA0825 |
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| Organism | Homo sapiens |
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| Length | 1275 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (39)
Diseases linked to this target (Open Targets).
- postaxial polydactyly type A · score 0.66
- polydactyly, postaxial, type A1 · score 0.42
- mathematical ability · score 0.41
- self reported educational attainment · score 0.34
- BMI-adjusted waist circumference · score 0.33
- neurofibrillary tangles measurement · score 0.25
- neuroimaging measurement · score 0.23
- cortical thickness · score 0.22
- cortical surface area measurement · score 0.20
- brain measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IV33-F1 | alphafold | PREDICTED | 73.87 | — |
Amino-acid sequence (1275 residues)
MDWDDEYSHN SFDLHCLLNS FPGDLEFEQI FSDIDEKIEQ NAASIKHCIK EIQSEINKQC PGVQLQTTTD CFEWLTNYNY STSESSFISH GDLIKFFKTL QDLLKNEQNQ EEMTLDLLWD LSCHSSVSFP STLSGTSFHF LSRTSLHSVE DNSSMDVKSM WDDIRLHLRR FLVSKLQSHN EINNSQQKIL LKKQCLQQLL FLYPESEVII KYQNIQNKLL ANLLWNCFPS YNRDSNLDVI AHGYQSTMLK LYSVIKEDFN TLCEILAPSS MVKFIKETYL DTVTEEMAKF LENFCELQFR ENAVRVVKTS KSSSKHRGAV HALVTTECPQ KGRNFSLPLD KVEFLSQLIK SFMKLEKGVQ ELFDEILLSL KITRDTSGIL EKSDREVVME KPRANETNIP SEQSLPGKEA TLLDFGWRSA FKEVSLPMAH CVVTAIEGFS TKILQQEQNE RSSAVSYAMN LVNVQQVWQD SHMFPEEEQP KKIGKFCSDI MEKLDTMLPL ALACRDDSFQ EIRANLVEAC CKVATAVLQR LQERAKEVPS KAPLKNLHTY LSTAVYVFQH FKRYDNLMKE MTKKPIFLVL VQRYQEFINT LQFQVTNYCV RVCATSILQD AESHHWDDYK AFYEGERCSF SIQMWHYFCW SLHYDLWTIL PPKLAQEILV EVLEKSLSLL ASRYARAHPS RKRTPQLRLD VTTILICTEN MLWSVCTSVQ KLLNPHQHTD DKIFKIHTHC NNLFTTLVIL TSPLTELYKT FQHGLDESAS DSLKSFFKQP LYWVSCISHF YPSLLRTPSA GGLKAEGQLK LLLSQPRCNW NLLLETLLHH DGLLLRILLK SSKQVSDTEN NLNQGPSLME AIFKILYHCS FSPQTFANVF VSYMEEEQLW DFLYNIPVST CVEYELEVIR CLRLALTDAI KDTVQQIVSV MSSRRNCETN LNKHIVPDCL LESMPKEWNY SPKETNRKES CKSFTRLTAQ AVSIVISKLP TVIACLPPPV KYFFFLSERK MSKKFVELKK AGLLVWNLIV IICRIFEDGN TVELLTGASL DRWSKEKLGL ICMCLKSIMG DQTSIHNQMI QKVIQSIEQQ KPNWIERQLL KARKLSTECA FMTIEKSTAL QEGDVALELT EQKINTMVLD LCHKPGGREY LRQIYHIMQL NEEYLKEQLF SMNSSEEKPL PIRPLKTTLR SIEDQPSAFN PFHVYKAFSE NMLDQSAITK WNWNWAKLLP NYLRLDKMTF SVLLKNRWEM KKDETLEEEE KAILEHLKQI CTPQNSSASD NIEEQ
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