About Protein HID1
Protein HID1 (HID1) is a protein
from Homo sapiens identified by UniProt accession
Q8IV36, 788 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Protein HID1 |
|---|
| UniProt accession | Q8IV36 |
|---|
| Gene | HID1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 788 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy 105 with hypopituitarism · score 0.67
- hypopituitarism · score 0.51
- genetic disorder · score 0.33
- Barrett's esophagus · score 0.05
- breast cancer · score 0.05
- esophageal adenocarcinoma · score 0.03
- myeloid white cell count · score 0.02
- lymphocyte percentage of leukocytes · score 0.02
- neutrophil percentage of leukocytes · score 0.02
- Glucose intolerance · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IV36-F1 | alphafold | PREDICTED | 85.29 | — |
Amino-acid sequence (788 residues)
MGSTDSKLNF RKAVIQLTTK TQPVEATDDA FWDQFWADTA TSVQDVFALV PAAEIRAVRE ESPSNLATLC YKAVEKLVQG AESGCHSEKE KQIVLNCSRL LTRVLPYIFE DPDWRGFFWS TVPGAGRGGQ GEEDDEHARP LAESLLLAIA DLLFCPDFTV QSHRRSTVDS AEDVHSLDSC EYIWEAGVGF AHSPQPNYIH DMNRMELLKL LLTCFSEAMY LPPAPESGST NPWVQFFCST ENRHALPLFT SLLNTVCAYD PVGYGIPYNH LLFSDYREPL VEEAAQVLIV TLDHDSASSA SPTVDGTTTG TAMDDADPPG PENLFVNYLS RIHREEDFQF ILKGIARLLS NPLLQTYLPN STKKIQFHQE LLVLFWKLCD FNKKFLFFVL KSSDVLDILV PILFFLNDAR ADQSRVGLMH IGVFILLLLS GERNFGVRLN KPYSIRVPMD IPVFTGTHAD LLIVVFHKII TSGHQRLQPL FDCLLTIVVN VSPYLKSLSM VTANKLLHLL EAFSTTWFLF SAAQNHHLVF FLLEVFNNII QYQFDGNSNL VYAIIRKRSI FHQLANLPTD PPTIHKALQR RRRTPEPLSR TGSQEGTSME GSRPAAPAEP GTLKTSLVAT PGIDKLTEKS QVSEDGTLRS LEPEPQQSLE DGSPAKGEPS QAWREQRRPS TSSASGQWSP TPEWVLSWKS KLPLQTIMRL LQVLVPQVEK ICIDKGLTDE SEILRFLQHG TLVGLLPVPH PILIRKYQAN SGTAMWFRTY MWGVIYLRNV DPPVWYDTDV KLFEIQRV
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