About LysM and putative peptidoglycan-binding domain-containing protein 2
LysM and putative peptidoglycan-binding domain-containing protein 2 (LYSMD2) is a protein
from Homo sapiens identified by UniProt accession
Q8IV50, 215 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | LysM and putative peptidoglycan-binding domain-containing protein 2 |
| UniProt accession | Q8IV50 |
| Gene | LYSMD2 |
| Organism | Homo sapiens |
| Length | 215 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.18
- developmental and epileptic encephalopathy · score 0.12
- developmental and epileptic encephalopathy, 13 · score 0.12
- body mass index · score 0.10
- body height · score 0.10
- cortical surface area measurement · score 0.08
- lean body mass · score 0.08
- intelligence · score 0.07
- body fat percentage · score 0.07
- self reported educational attainment · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8IV50-F1 | alphafold | PREDICTED | 66.94 | — |
Amino-acid sequence (215 residues)
MADSSPALSL REGGPRAPRP SAPSPPPRSR SGSESEEAEL SLSLARTKTR SYGSTASVRA PLGAGVIERH VEHRVRAGDT LQGIALKYGV TMEQIKRANK LFTNDCIFLK KTLNIPVISE KPLLFNGLNS IDSPENETAD NSFSQEEEPV VAGEDLPPPS PQESDVQPVQ PEEVSARDFL QRLDLQIKLS TQAAKKLKEE SRDEESPYAT SLYHS
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