Purkinje cell protein 2 homolog (PCP2)

About Purkinje cell protein 2 homolog

Purkinje cell protein 2 homolog (PCP2) is a protein from Homo sapiens identified by UniProt accession Q8IVA1, 136 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Purkinje cell protein 2 homolog
UniProt accession	Q8IVA1
Gene	PCP2
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neuropathic pain · score 0.16
neoplasm · score 0.00
astrocytoma · score 0.00
Fibroadenoma · score 0.00
cancer · score 0.00
endometrial carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IVA1-F1	alphafold	PREDICTED	69.87	—

Amino-acid sequence (136 residues)

MMDQEEKTEE GSGPCAEAGS PDQEGFFNLL SHVQGDRMEG QRCSLQAGPG QTTKSQSDPT PEMDSLMDML ASTQGRRMDD QRVTVSSLPG FQPVGSKDGA QKRAGTLSPQ PLLTPQDPTA LGFRRNSSPQ PPTQAP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards