About LIX1-like protein
LIX1-like protein (LIX1L) is a protein
from Homo sapiens identified by UniProt accession
Q8IVB5, 337 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | LIX1-like protein |
|---|
| UniProt accession | Q8IVB5 |
|---|
| Gene | LIX1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 337 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- neutrophil count · score 0.08
- hepatocellular carcinoma · score 0.08
- cancer · score 0.08
- non-small cell lung carcinoma · score 0.07
- neurogenic locus notch homolog protein 2 measurement · score 0.07
- neoplasm · score 0.04
- ovarian carcinoma · score 0.02
- breast cancer · score 0.02
- Down syndrome · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVB5-F1 | alphafold | PREDICTED | 78.17 | — |
Amino-acid sequence (337 residues)
METMRAQRLQ PGVGTSGRGT LRALRPGVTG AAAATATPPA GPPPAPPPPA PPPPPLLLSG APGLPLPPGA AGSPAVLREA VEAVVRSFAK HTQGYGRVNV VEALQEFWQM KQSRGADLKN GALVVYEMVP SNSPPYVCYV TLPGGSCFGS FQFCPTKAEA RRSAAKIALM NSVFNEHPSR RITDEFIEKS VSEALASFNG NREEADNPNT GIGAFRFMLE SNKGKSMLEF QELMTVFQLL HWNGSLKAMR ERQCSRQEVL AHYSHRALDD DIRHQMALDW VSREQSVPGA LSRELASTER ELDEARLAGK ELRFHKEKKD ILVLAAGQLG NMHSSNC
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