Zinc finger protein 584 (ZNF584)

About Zinc finger protein 584

Zinc finger protein 584 (ZNF584) is a protein from Homo sapiens identified by UniProt accession Q8IVC4, 421 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Zinc finger protein 584
UniProt accession	Q8IVC4
Gene	ZNF584
Organism	Homo sapiens
Length	421 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

platelet count · score 0.33
mean platelet volume · score 0.29
platelet component distribution width · score 0.21
platelet crit · score 0.14
puberty onset measurement · score 0.12
mean corpuscular volume · score 0.06
age at menarche · score 0.04
Dyspnea · score 0.03
cognitive function measurement · score 0.02
attention deficit hyperactivity disorder · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IVC4-F1	alphafold	PREDICTED	64.78	—

Amino-acid sequence (421 residues)

MAGEAEAQLD PSLQGLVMFE DVTVYFSREE WGLLNVTQKG LYRDVMLENF ALVSSLGLAP SRSPVFTQLE DDEQSWVPSW VDVTPVSRAE ARRGFGLDGL CRVEDERAHP EHLKSYRVIQ HQDTHSEGKP RRHTEHGAAF PPGSSCGQQQ EVHVAEKLFK CSDCGKVFLK AFALLDHLIT HSEERPFRCP TGRSAFKKSA HINPRKIHTG ETAHVCNECG KAFSYPSKLR KHQKVHTGIK PFKCSDCGKT FNRKDALVLH QRIHTGERPY ECSKCGKTFS VLSTLIRHRK VHIGERPYEC TECGKFFKYN NSFILHQRVH TGERPFECKQ CGKGYVTRSG LYQHWKVHTG ERPYECSLCG KTFTTRSYRN RHQQFHTEER SYECTECGKA FKHSSTLLQH KKVHTPERRQ EDRAHGKVVS C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards