Nostrin (NOSTRIN)

About Nostrin

Nostrin (NOSTRIN) is a protein from Homo sapiens identified by UniProt accession Q8IVI9, 506 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.

Target properties

Protein name	Nostrin
UniProt accession	Q8IVI9
Gene	NOSTRIN
Organism	Homo sapiens
Length	506 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (98)

Diseases linked to this target (Open Targets).

monocyte count · score 0.43
leukocyte count · score 0.41
eosinophil count · score 0.40
neutrophil count · score 0.40
body height · score 0.40
lymphocyte count · score 0.37
myeloid white cell count · score 0.36
appendicular lean mass · score 0.35
forced expiratory volume · score 0.33
lean body mass · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IVI9-F1	alphafold	PREDICTED	86.53	—

Amino-acid sequence (506 residues)

MRDPLTDCPY NKVYKNLKEF SQNGENFCKQ VTSVLQQRAN LEISYAKGLQ KLASKLSKAL QNTRKSCVSS AWAWASEGMK STADLHQKLG KAIELEAIKP TYQVLNVQEK KRKSLDNEVE KTANLVISNW NQQIKAKKKL MVSTKKHEAL FQLVESSKQS MTEKEKRKLL NKLTKSTEKL EKEDENYYQK NMAGYSTRLK WENTLENCYQ SILELEKERI QLLCNNLNQY SQHISLFGQT LTTCHTQIHC AISKIDIEKD IQAVMEETAI LSTENKSEFL LTDYFEEDPN SAMDKERRKS LLKPKLLRLQ RDIEKASKDK EGLERMLKTY SSTSSFSDAK SQKDTAALMD ENNLKLDLLE ANSYKLSSML AELEQRPQPS HPCSNSIFRW REKEHTHSYV KISRPFLMKR LENIVSKASS GGQSNPGSST PAPGAAQLSS RLCKALYSFQ ARQDDELNLE KGDIVIIHEK KEGGWWFGSL NGKKGHFPAA YVEELPSNAG NTATKA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards