About Coiled-coil domain-containing protein 50
Coiled-coil domain-containing protein 50 (CCDC50) is a protein
from Homo sapiens identified by UniProt accession
Q8IVM0, 306 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 50 |
|---|
| UniProt accession | Q8IVM0 |
|---|
| Gene | CCDC50 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 306 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- autosomal dominant nonsyndromic hearing loss · score 0.55
- deafness · score 0.55
- neurodegenerative disease · score 0.43
- hearing loss · score 0.37
- serum gamma-glutamyl transferase measurement · score 0.26
- body height · score 0.25
- Blackfan-Diamond anemia · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.08
- hepatocellular carcinoma · score 0.08
- diffuse large B-cell lymphoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVM0-F1 | alphafold | PREDICTED | 75.75 | — |
Amino-acid sequence (306 residues)
MAEVSIDQSK LPGVKEVCRD FAVLEDHTLA HSLQEQEIEH HLASNVQRNR LVQHDLQVAK QLQEEDLKAQ AQLQKRYKDL EQQDCEIAQE IQEKLAIEAE RRRIQEKKDE DIARLLQEKE LQEEKKRKKH FPEFPATRAY ADSYYYEDGG MKPRVMKEAV STPSRMAHRD QEWYDAEIAR KLQEEELLAT QVDMRAAQVA QDEEIARLLM AEEKKAYKKA KEREKSSLDK RKQDPEWKPK TAKAANSKSK ESDEPHHSKN ERPARPPPPI MTDGEDADYT HFTNQQSSTR HFSKSESSHK GFHYKH
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