About Organic anion transporter 7
Organic anion transporter 7 (SLC22A9) is a protein
from Homo sapiens identified by UniProt accession
Q8IVM8, 553 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Organic anion transporter 7 |
|---|
| UniProt accession | Q8IVM8 |
|---|
| Gene | SLC22A9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 553 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- hypertrophic cardiomyopathy · score 0.14
- glycoprotein storage disease · score 0.05
- central nervous system cancer · score 0.05
- neuronal ceroid lipofuscinosis 1 · score 0.04
- hemoglobin H disease · score 0.04
- hemoglobin C-beta-thalassemia syndrome · score 0.04
- combined immunodeficiency due to OX40 deficiency · score 0.04
- familial isolated congenital asplenia · score 0.04
- Hyperlipoproteinemia type 1 · score 0.04
- dominant beta-thalassemia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVM8-F1 | alphafold | PREDICTED | 85.68 | — |
Amino-acid sequence (553 residues)
MAFQDLLGHA GDLWRFQILQ TVFLSIFAVA TYLHFMLENF TAFIPGHRCW VHILDNDTVS DNDTGALSQD ALLRISIPLD SNMRPEKCRR FVHPQWQLLH LNGTFPNTSD ADMEPCVDGW VYDRISFSST IVTEWDLVCD SQSLTSVAKF VFMAGMMVGG ILGGHLSDRF GRRFVLRWCY LQVAIVGTCA ALAPTFLIYC SLRFLSGIAA MSLITNTIML IAEWATHRFQ AMGITLGMCP SGIAFMTLAG LAFAIRDWHI LQLVVSVPYF VIFLTSSWLL ESARWLIINN KPEEGLKELR KAAHRSGMKN ARDTLTLEIL KSTMKKELEA AQKKKPSLCE MLHMPNICKR ISLLSFTRFA NFMAYFGLNL HVQHLGNNVF LLQTLFGAVI LLANCVAPWA LKYMNRRASQ MLLMFLLAIC LLAIIFVPQE MQTLREVLAT LGLGASALAN TLAFAHGNEV IPTIIRARAM GINATFANIA GALAPLMMIL SVYSPPLPWI IYGVFPFISG FAFLLLPETR NKPLFDTIQD EKNERKDPRE PKQEDPRVEV TQF
Explore Organic anion transporter 7 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets