About Zinc finger protein 547
Zinc finger protein 547 (ZNF547) is a protein
from Homo sapiens identified by UniProt accession
Q8IVP9, 402 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 547 |
|---|
| UniProt accession | Q8IVP9 |
|---|
| Gene | ZNF547 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 402 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- refractive error · score 0.14
- fat body mass · score 0.06
- platelet count · score 0.06
- lean body mass · score 0.06
- appendicular lean mass · score 0.04
- colorectal neoplasm · score 0.00
- Sjogren syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVP9-F1 | alphafold | PREDICTED | 68.87 | — |
Amino-acid sequence (402 residues)
MAEMNPAQGH VVFEDVAIYF SQEEWGHLDE AQRLLYRDVM LENLALLSSL GCCHGAEDEE APLEPGVSVG VSQVMAPKPC LSTQNTQPCE TCSSLLKDIL RLAEHDGTHP EQGLYTCPAH LHQHQKEQIR EKLSRGDGGR PTFVKNHRVH MAGKTFLCSE CGKAFSHKHK LSDHQKIHTG ERTYKCSKCG ILFMERSTLN RHQRTHTGER PYECNECGKA FLCKSHLVRH QTIHSGERPY ECSECGKLFM WSSTLITHQR VHTGKRPYGC SECGKFFKCN SNLFRHYRIH TGKRSYGCSE CGKFFMERST LSRHQRVHTG ERPYECNECG KFFSLKSVLI QHQRVHTGER PYECSECGKA FLTKSHLICH QTVHTAAKQC SECGKFFRYN STLLRHQKVH TG
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