About Immunoglobulin superfamily DCC subclass member 3
Immunoglobulin superfamily DCC subclass member 3 (IGDCC3) is a protein
from Homo sapiens identified by UniProt accession
Q8IVU1, 814 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Immunoglobulin superfamily DCC subclass member 3 |
|---|
| UniProt accession | Q8IVU1 |
|---|
| Gene | IGDCC3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 814 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.30
- protein measurement · score 0.16
- mean corpuscular hemoglobin concentration · score 0.07
- mean corpuscular volume · score 0.07
- breast carcinoma · score 0.04
- mean corpuscular hemoglobin · score 0.02
- hepatocellular carcinoma · score 0.01
- cholangiocarcinoma · score 0.00
- primitive neuroectodermal tumor · score 0.00
- breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVU1-F1 | alphafold | PREDICTED | 74.41 | — |
Amino-acid sequence (814 residues)
MAVQRAASPR RPPAPLWPRL LLPLLLLLLP APSEGLGHSA ELAFAVEPSD DVAVPGQPIV LDCRVEGTPP VRITWRKNGV ELPESTHSTL LANGSLMIRH FRLEPGGSPS DEGDYECVAQ NRFGLVVSRK ARIQAATMSD FHVHPQATVG EEGGVARFQC QIHGLPKPLI TWEKNRVPID TDNERYTLLP KGVLQITGLR AEDGGIFHCV ASNIASIRIS HGARLTVSGS GSGAYKEPAI LVGPENLTLT VHQTAVLECV ATGNPRPIVS WSRLDGRPIG VEGIQVLGTG NLIISDVTVQ HSGVYVCAAN RPGTRVRRTA QGRLVVQAPA EFVQHPQSIS RPAGTTAMFT CQAQGEPPPH VTWLKNGQVL GPGGHVRLKN NNSTLTISGI GPEDEAIYQC VAENSAGSSQ ASARLTVLWA EGLPGPPRNV RAVSVSSTEV RVSWSEPLAN TKEIIGYVLH IRKAADPPEL EYQEAVSKST FQHLVSDLEP STAYSFYIKA YTPRGASSAS VPTLASTLGE APAPPPLSVR VLGSSSLQLL WEPWPRLAQH EGGFKLFYRP ASKTSFTGPI LLPGTVSSYN LSQLDPTAVY EVKLLAYNQH GDGNATVRFV SLRGASERTA LSPPCDCRKE EAANQTSTTG IVIGIHIGVT CIIFCVLFLL FGQRGRVLLC KDVENQLSPP QGPRSQRDPG ILALNGARRG QRGQLGRDEK RVDMKELEQL FPPASAAGQP DPRPTQDPAA PAPCEETQLS VLPLQGCGLM EGKTTEAKTT EATAPCAGLA AAPPPPDGGP GLLSEGQASR PAAARVTQPA HSEQ
Explore Immunoglobulin superfamily DCC subclass member 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets