About Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 (NKAIN4) is a protein
from Homo sapiens identified by UniProt accession
Q8IVV8, 208 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 |
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| UniProt accession | Q8IVV8 |
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| Gene | NKAIN4 |
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| Organism | Homo sapiens |
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| Length | 208 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.07
- atypical teratoid rhabdoid tumor · score 0.02
- autism · score 0.02
- astrocytoma · score 0.01
- Alzheimer disease · score 0.01
- cancer · score 0.01
- clear cell renal carcinoma · score 0.01
- oligodendroglioma · score 0.01
- papillary thyroid carcinoma · score 0.01
- small cell lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVV8-F1 | alphafold | PREDICTED | 70.69 | — |
Amino-acid sequence (208 residues)
MGSCSGRCAL VVLCAFQLVA ALERQVFDFL GYQWAPILAN FVHIIIVILG LFGTIQYRLR YVMVYTLWAA VWVTWNVFII CFYLEVGGLL KDSELLTFSL SRHRSWWRER WPGCLHEEVP AVGLGAPHGQ ALVSGAGCAL EPSYVEALHS CLQILIALLG FVCGCQVVSV FTEEEDSFDF IGGFDPFPLY HVNEKPSSLL SKQVYLPA
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