About Putative ADP-ribosylation factor-like protein 17A
Putative ADP-ribosylation factor-like protein 17A (ARL17A) is a protein
from Homo sapiens identified by UniProt accession
Q8IVW1, 177 residues long.
MolForge cross-references it against 0 known binders and
133 disease associations.
Target properties
| Protein name | Putative ADP-ribosylation factor-like protein 17A |
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| UniProt accession | Q8IVW1 |
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| Gene | ARL17A |
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| Organism | Homo sapiens |
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| Length | 177 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (133)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.38
- mean corpuscular volume · score 0.37
- neurodegenerative disease · score 0.36
- Koolen-de Vries syndrome · score 0.34
- brain measurement · score 0.31
- neutrophil count · score 0.31
- reticulocyte count · score 0.29
- mean corpuscular hemoglobin concentration · score 0.26
- BMI-adjusted waist-hip ratio · score 0.26
- body height · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVW1-F1 | alphafold | PREDICTED | 53.41 | — |
Amino-acid sequence (177 residues)
MGNIFEKLFK SLLGKKKMRI LILSLDTAGK TTILYKLKLG ETVPAVPTVG FCVETVEYKN NTFAVWDVGS HFKIRPLWQH FFQNTKGARS PGSTHQGSLA SGVLPIKCSH VEFGMWKGGR SHPFLPHSSR CAGSGGQLDS ILPHQSPAWG PWGCKDLSSG FPSFLTSSIL WKSAVVK
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