About AT-rich interactive domain-containing protein 3B
AT-rich interactive domain-containing protein 3B (ARID3B) is a protein
from Homo sapiens identified by UniProt accession
Q8IVW6, 561 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | AT-rich interactive domain-containing protein 3B |
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| UniProt accession | Q8IVW6 |
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| Gene | ARID3B |
|---|
| Organism | Homo sapiens |
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| Length | 561 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (62)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.18
- cleft lip · score 0.14
- Cleft palate · score 0.14
- eosinophil percentage of leukocytes · score 0.12
- high density lipoprotein cholesterol measurement · score 0.12
- sitting height measurement · score 0.11
- neoplasm · score 0.10
- eosinophil count · score 0.09
- urinary bladder carcinoma · score 0.07
- gonorrhea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IVW6-F1 | alphafold | PREDICTED | 57.98 | — |
Amino-acid sequence (561 residues)
MEPLQQQQQQ QQQQQKQPHL APLQMDAREK QGQQMREAQF LYAQKLVTQP TLLSATAGRP SGSTPLGPLA RVPPTAAVAQ VFERGNMNSE PEEEDGGLED EDGDDEVAEV AEKETQAASK YFHVQKVARQ DPRVAPMSNL LPAPGLPPHG QQAKEDHTKD ASKASPSVST AGQPNWNLDE QLKQNGGLAW SDDADGGRGR EISRDFAKLY ELDGDPERKE FLDDLFVFMQ KRGTPINRIP IMAKQILDLY MLYKLVTEKG GLVEIINKKI WREITKGLNL PTSITSAAFT LRTQYMKYLY AYECEKKALS SPAELQAAID GNRREGRRPS YSSSLFGYSP AAATAAAAAG APALLSPPKI RFPILGLGSS SGTNTSSPRI SPATTLRKGD GAPVTTVPVP NRLAVPVTLA SQQAGTRTAA LEQLRERLES GEPAEKKASR LSEEEQRLVQ QAFQRNFFSM ARQLPMKIRI NGRAEDRAEA SAAALNLTTS SIGSINMSVD IDGTTYAGVL FAQKPVVHLI TGSAPQSLGS SASSSSSSHC SPSPTSSRGT PSAEPSTSWS L
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