About Beta-galactosidase-1-like protein 2
Beta-galactosidase-1-like protein 2 (GLB1L2) is a protein
from Homo sapiens identified by UniProt accession
Q8IW92, 636 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Beta-galactosidase-1-like protein 2 |
|---|
| UniProt accession | Q8IW92 |
|---|
| Gene | GLB1L2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 636 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- body mass index · score 0.13
- body fat percentage · score 0.13
- schizophrenia · score 0.12
- fat body mass · score 0.12
- lean body mass · score 0.10
- alkaline phosphatase measurement · score 0.10
- body weight · score 0.10
- Age-related cataract · score 0.09
- body height · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IW92-F1 | alphafold | PREDICTED | 94.00 | — |
Amino-acid sequence (636 residues)
MTTWSLRRRP ARTLGLLLLV VLGFLVLRRL DWSTLVPLRL RHRQLGLQAK GWNFMLEDST FWIFGGSIHY FRVPREYWRD RLLKMKACGL NTLTTYVPWN LHEPERGKFD FSGNLDLEAF VLMAAEIGLW VILRPGPYIC SEMDLGGLPS WLLQDPGMRL RTTYKGFTEA VDLYFDHLMS RVVPLQYKRG GPIIAVQVEN EYGSYNKDPA YMPYVKKALE DRGIVELLLT SDNKDGLSKG IVQGVLATIN LQSTHELQLL TTFLFNVQGT QPKMVMEYWT GWFDSWGGPH NILDSSEVLK TVSAIVDAGS SINLYMFHGG TNFGFMNGAM HFHDYKSDVT SYDYDAVLTE AGDYTAKYMK LRDFFGSISG IPLPPPPDLL PKMPYEPLTP VLYLSLWDAL KYLGEPIKSE KPINMENLPV NGGNGQSFGY ILYETSITSS GILSGHVHDR GQVFVNTVSI GFLDYKTTKI AVPLIQGYTV LRILVENRGR VNYGENIDDQ RKGLIGNLYL NDSPLKNFRI YSLDMKKSFF QRFGLDKWSS LPETPTLPAF FLGSLSISST PCDTFLKLEG WEKGVVFING QNLGRYWNIG PQKTLYLPGP WLSSGINQVI VFEETMAGPA LQFTETPHLG RNQYIK
Explore Beta-galactosidase-1-like protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets