Major facilitator superfamily domain-containing protein 6-like (MFSD6L)

Homo sapiens — UniProt Q8IWD5

Gene: MFSD6LHomo sapiensSwissProt reviewed

About Major facilitator superfamily domain-containing protein 6-like

Major facilitator superfamily domain-containing protein 6-like (MFSD6L) is a protein from Homo sapiens identified by UniProt accession Q8IWD5, 586 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein nameMajor facilitator superfamily domain-containing protein 6-like
UniProt accessionQ8IWD5
GeneMFSD6L
OrganismHomo sapiens
Length586 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8IWD5-F1alphafoldPREDICTED74.18—

Amino-acid sequence (586 residues)

MSANPRWDIS RALGVAKLFH LVCGVREACV TPFLTLYLRQ LGLAAPWVGT LMGTKHLIAA FWAPVCAFLA KSYRKRRALL IGSLLGSVGA SLLMVLVPPV DKNRVHFPCN GSSGLTSTDA LPGVTLPVNI TSAQESASSH PAKRTAEVEM PGFRNPPGES DRETFRDLHV YLAPSVEGAR TTSQALLHPV TSGLKDHPWE VTFEVVKTAL PLLPGGKGPG NPANLSGTKG KAWAFDLSLE ALRRTFILSL GSVAFWELLT APLEQVADDS LYEFLDFVDA TDRYRSLWVW RLLGMSAGVC GITALVGQLD CFLMTSGPRG VVHFYGYSVV STLALLVSIA FPIPICQQWE PSYKRVKALS IVGGDPHLIL LASTTVLVGA IVSTVQNFLF WHMKDHGSGE LVMGFSVALS LLGEILLHPF KATLLRKLSR TGLVGLGLSC LAGQLLYYSF LWSWWSVLPI QILSAISNRA LWWAVGASVE DLATPRMERA LSALFRGHFY GSGCSLGSFV GGFVVMRFSL AVLYQACCVA LLLWLALLLS IQRRLPRERK IKYSKLLSME VSDTSDSEQG TEQDWLVKAM REEHSD

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Quick facts

UniProtQ8IWD5
GeneMFSD6L
OrganismHomo sapiens
Length586
Binders0
Diseases11
View on UniProt