Protein NOXP20 (FAM114A1)

About Protein NOXP20

Protein NOXP20 (FAM114A1) is a protein from Homo sapiens identified by UniProt accession Q8IWE2, 563 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.

Target properties

Protein name	Protein NOXP20
UniProt accession	Q8IWE2
Gene	FAM114A1
Organism	Homo sapiens
Length	563 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (88)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.34
mean corpuscular volume · score 0.33
bilirubin measurement · score 0.32
body height · score 0.30
mean corpuscular hemoglobin · score 0.30
mean corpuscular hemoglobin concentration · score 0.29
mean reticulocyte volume · score 0.27
red blood cell density measurement · score 0.26
lymphocyte count · score 0.22
asthma · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IWE2-F1	alphafold	PREDICTED	63.59	—

Amino-acid sequence (563 residues)

MSDDAGDTLA TGDKAEVTEM PNSDSLPEDA EVHCDSAAVS HEPTPADPRG EGHENAAVQG AGAAAIGPPV QPQDANALEP PLNGDVTEDT LAECIDSVSL EAEPRSEIPL QEQNYLAVDS PPSGGGWAGW GSWGKSLLSS ASATVGHGLT AVKEKAGATL RIHGVNSGSS EGAQPNTENG VPEITDAATD QGPAESPPTS PSSASRGMLS AITNVVQNTG KSVLTGGLDA LEFIGKKTMN VLAESDPGFK RTKTLMERTV SLSQMLREAK EKEKQRLAQQ LTMERTAHYG MLFDEYQGLS HLEALEILSN ESESKVQSFL ASLDGEKLEL LKNDLISIKD IFAAKELENE ENQEEQGLEE KGEEFARMLT ELLFELHVAA TPDKLNKAMK RAHDWVEEDQ TVVSVDVAKV SEEETKKEEK EEKSQDPQED KKEEKKTKTI EEVYMSSIES LAEVTARCIE QLHKVAELIL HGQEEEKPAQ DQAKVLIKLT TAMCNEVASL SKKFTNSLTT VGSNKKAEVL NPMISSVLLE GCNSTTYIQD AFQLLLPVLQ VSHIQTSCLK AQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards