About Mast cell-expressed membrane protein 1
Mast cell-expressed membrane protein 1 (MCEMP1) is a protein
from Homo sapiens identified by UniProt accession
Q8IX19, 187 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Mast cell-expressed membrane protein 1 |
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| UniProt accession | Q8IX19 |
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| Gene | MCEMP1 |
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| Organism | Homo sapiens |
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| Length | 187 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (62)
Diseases linked to this target (Open Targets).
- resistin measurement · score 0.21
- COVID-19 · score 0.08
- immature platelet fraction · score 0.06
- Crohn's disease · score 0.05
- non-small cell lung carcinoma · score 0.05
- Sepsis · score 0.04
- eosinophil peroxidase deficiency · score 0.04
- ulcerative colitis · score 0.04
- neutropenia, severe congenital, 1, autosomal dominant · score 0.04
- chronic myeloproliferative disorder · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IX19-F1 | alphafold | PREDICTED | 75.01 | — |
Amino-acid sequence (187 residues)
MEVEEIYKHQ EVKMQAPAFR DKKQGVSAKN QGAHDPDYEN ITLAFKNQDH AKGGHSRPTS QVPAQCRPPS DSTQVPCWLY RAILSLYILL ALAFVLCIIL SAFIMVKNAE MSKELLGFKR ELWNVSNSVQ ACEERQKRGW DSVQQSITMV RSKIDRLETT LAGIKNIDTK VQKILEVLQK MPQSSPQ
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