About SMC5-SMC6 complex localization factor protein 2
SMC5-SMC6 complex localization factor protein 2 (SLF2) is a protein
from Homo sapiens identified by UniProt accession
Q8IX21, 1173 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | SMC5-SMC6 complex localization factor protein 2 |
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| UniProt accession | Q8IX21 |
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| Gene | SLF2 |
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| Organism | Homo sapiens |
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| Length | 1173 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IX21-F1 | alphafold | PREDICTED | 55.02 | — |
Amino-acid sequence (1173 residues)
MTRRCMPARP GFPSSPAPGS SPPRCHLRPG STAHAAAGKR TESPGDRKQS IIDFFKPASK QDRHMLDSPQ KSNIKYGGSR LSITGTEQFE RKLSSPKESK PKRVPPEKSP IIEAFMKGVK EHHEDHGIHE SRRPCLSLAS KYLAKGTNIY VPSSYHLPKE MKSLKKKHRS PERRKSLFIH ENNEKNDRDR GKTNADSKKQ TTVAEADIFN NSSRSLSSRS SLSRHHPEES PLGAKFQLSL ASYCRERELK RLRKEQMEQR INSENSFSEA SSLSLKSSIE RKYKPRQEQR KQNDIIPGKN NLSNVENGHL SRKRSSSDSW EPTSAGSKQN KFPEKRKRNS VDSDLKSTRE SMIPKARESF LEKRPDGPHQ KEKFIKHIAL KTPGDVLRLE DISKEPSDET DGSSAGLAPS NSGNSGHHST RNSDQIQVAG TKETKMQKPH LPLSQEKSAI KKASNLQKNK TASSTTKEKE TKLPLLSRVP SAGSSLVPLN AKNCALPVSK KDKERSSSKE CSGHSTESTK HKEHKAKTNK ADSNVSSGKI SGGPLRSEYG TPTKSPPAAL EVVPCIPSPA APSDKAPSEG ESSGNSNAGS SALKRKLRGD FDSDEESLGY NLDSDEEEET LKSLEEIMAL NFNQTPAATG KPPALSKGLR SQSSDYTGHV HPGTYTNTLE RLVKEMEDTQ RLDELQKQLQ EDIRQGRGIK SPIRIGEEDS TDDEDGLLEE HKEFLKKFSV TIDAIPDHHP GEEIFNFLNS GKIFNQYTLD LRDSGFIGQS AVEKLILKSG KTDQIFLTTQ GFLTSAYHYV QCPVPVLKWL FRMMSVHTDC IVSVQILSTL MEITIRNDTF SDSPVWPWIP SLSDVAAVFF NMGIDFRSLF PLENLQPDFN EDYLVSETQT TSRGKESEDS SYKPIFSTLP ETNILNVVKF LGLCTSIHPE GYQDREIMLL ILMLFKMSLE KQLKQIPLVD FQSLLINLMK NIRDWNTKVP ELCLGINELS SHPHNLLWLV QLVPNWTSRG RQLRQCLSLV IISKLLDEKH EDVPNASNLQ VSVLHRYLVQ MKPSDLLKKM VLKKKAEQPD GIIDDSLHLE LEKQAYYLTY ILLHLVGEVS CSHSFSSGQR KHFVLLCGAL EKHVKCDIRE DARLFYRTKV KDLVARIHGK WQEIIQNCRP TQGQLHDFWV PDS
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