About F-box only protein 16
F-box only protein 16 (FBXO16) is a protein
from Homo sapiens identified by UniProt accession
Q8IX29, 292 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | F-box only protein 16 |
|---|
| UniProt accession | Q8IX29 |
|---|
| Gene | FBXO16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.31
- brain measurement · score 0.30
- neoplasm · score 0.08
- birth weight · score 0.06
- adolescent idiopathic scoliosis · score 0.06
- glioblastoma multiforme · score 0.04
- cortical thickness · score 0.04
- lung carcinoma · score 0.02
- breast cancer · score 0.02
- body mass index · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IX29-F1 | alphafold | PREDICTED | 70.66 | — |
Amino-acid sequence (292 residues)
MMAFAPPKNT DGPKMQTKMS TWTPLNHQLL NDRVFEERRA LLGKWFDKWT DSQRRRILTG LLERCSLSQQ KFCCRKLQEK IPAEALDFTT KLPRVLSLYI FSFLDPRSLC RCAQVCWHWK NLAELDQLWM LKCLRFNWYI NFSPTPFEQG IWKKHYIQMV KELHITKPKT PPKDGFVIAD VQLVTSNSPE EKQSPLSAFR SSSSLRKKNN SGEKALPPWR SSDKHPTDII RFNYLDNRDP METVQQGRRK RNQMTPDFSR QSHDKKNKLQ DRTRLRKAQS MMSRRNPFPL CP
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