Sperm acrosome membrane-associated protein 3 (SPACA3)

About Sperm acrosome membrane-associated protein 3

Sperm acrosome membrane-associated protein 3 (SPACA3) is a protein from Homo sapiens identified by UniProt accession Q8IXA5, 215 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Sperm acrosome membrane-associated protein 3
UniProt accession	Q8IXA5
Gene	SPACA3
Organism	Homo sapiens
Length	215 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXA5-F1	alphafold	PREDICTED	81.02	—

Amino-acid sequence (215 residues)

MVSALRGAPL IRVHSSPVSS PSVSGPRRLV SCLSSQSSAL SQSGGGSTSA AGIEARSRAL RRRWCPAGIM LLALVCLLSC LLPSSEAKLY GRCELARVLH DFGLDGYRGY SLADWVCLAY FTSGFNAAAL DYEADGSTNN GIFQINSRRW CSNLTPNVPN VCRMYCSDLL NPNLKDTVIC AMKITQEPQG LGYWEAWRHH CQGKDLTEWV DGCDF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards