About Olfactory receptor 4N5
Olfactory receptor 4N5 (OR4N5) is a protein
from Homo sapiens identified by UniProt accession
Q8IXE1, 308 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 4N5 |
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| UniProt accession | Q8IXE1 |
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| Gene | OR4N5 |
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| Organism | Homo sapiens |
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| Length | 308 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- ovarian cancer · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- insomnia · score 0.06
- total blood protein measurement · score 0.06
- monocyte count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IXE1-F1 | alphafold | PREDICTED | 88.05 | — |
Amino-acid sequence (308 residues)
METQNLTVVT EFILLGLTQS QDAQLLVFVL VLIFYLIILP GNFLIIFTIK SDPGLTAPLY FFLGNLALLD ASYSFIVVPR MLVDFLSEKK VISYRSCITQ LFFLHFLGAG EMFLLVVMAF DRYIAICRPL HYSTIMNPRA CYALSLVLWL GGFIHSIVQV ALILHLPFCG PNQLDNFFCD VPQVIKLACT NTFVVELLMV SNSGLLSLLC FLGLLASYAV ILCRIREHSS EGKSKAISTC TTHIIIIFLM FGPAIFIYTC PFQAFPADKV VSLFHTVIFP LMNPVIYTLR NQEVKASMRK LLSQHMFC
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