Putative aquaporin-12A (AQP12A)

About Putative aquaporin-12A

Putative aquaporin-12A (AQP12A) is a protein from Homo sapiens identified by UniProt accession Q8IXF9, 295 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Putative aquaporin-12A
UniProt accession	Q8IXF9
Gene	AQP12A
Organism	Homo sapiens
Length	295 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXF9-F1	alphafold	PREDICTED	78.31	—

Amino-acid sequence (295 residues)

MAGLNVSLSF FFATFALCEA ARRASKALLP VGAYEVFARE AMRTLVELGP WAGDFGPDLL LTLLFLLFLA HGVTLDGASA NPTVSLQEFL MAEQSLPGTL LKLAAQGLGM QAACTLMRLC WAWELSDLHL LQSLMAQSCS SALRTSVPHG ALVEAACAFC FHLTLLHLRH SPPAYSGPAV ALLVTVTAYT AGPFTSAFFN PALAASVTFA CSGHTLLEYV QVYWLGPLTG MVLAVLLHQG RLPHLFQRNL FYGQKNKYRA PRGKPAPASG DTQTPAKGSS VREPGRSGVE GPHSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards