About Tumor protein p53-inducible nuclear protein 2
Tumor protein p53-inducible nuclear protein 2 (TP53INP2) is a protein
from Homo sapiens identified by UniProt accession
Q8IXH6, 220 residues long.
MolForge cross-references it against 0 known binders and
110 disease associations.
Target properties
| Protein name | Tumor protein p53-inducible nuclear protein 2 |
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| UniProt accession | Q8IXH6 |
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| Gene | TP53INP2 |
|---|
| Organism | Homo sapiens |
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| Length | 220 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (110)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- Irritability · score 0.11
- calcium measurement · score 0.10
- hair color · score 0.09
- forced expiratory volume · score 0.09
- heel bone mineral density · score 0.09
- bone quantitative ultrasound measurement · score 0.08
- acute myeloid leukemia · score 0.08
- body height · score 0.08
- urate measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IXH6-F1 | alphafold | PREDICTED | 63.86 | — |
Amino-acid sequence (220 residues)
MFQRLSSLFF STPSPPEDPD CPRAFVSEED EVDGWLIIDL PDSYAAPPSP GAAPAPAGRP PPAPSLMDES WFVTPPACFT AEGPGLGPAR LQSSPLEDLL IEHPSMSVYV TGSTIVLEPG SPSPLPDAAL PDGDLSEGEL TPARREPRAA RHAAPLPARA ALLEKAGQVR RLQRARQRAE RHALSAKAVQ RQNRARESRP RRSKNQSSFI YQPCQRQFNY
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