IQ domain-containing protein F2 (IQCF2)

About IQ domain-containing protein F2

IQ domain-containing protein F2 (IQCF2) is a protein from Homo sapiens identified by UniProt accession Q8IXL9, 164 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	IQ domain-containing protein F2
UniProt accession	Q8IXL9
Gene	IQCF2
Organism	Homo sapiens
Length	164 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

sporadic amyotrophic lateral sclerosis · score 0.02
Abnormal sperm morphology · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXL9-F1	alphafold	PREDICTED	89.01	—

Amino-acid sequence (164 residues)

MRVRFCTKGN LILVIIEDVE ESIEWKTLQK KKQQKIKEKL RIRTKAAVKI QAWWRGTLVR RTLLHAALRA WIIQCWWRMT LSRVLEKKRQ AALIAYATRE RAVIKLQSLV RMWRVRWRYC QVLNAIYIIQ GHWQCHNCQT CALLQGHCVV TATHLQFHIE IINS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards