About BPTF-associated chromatin complex component 1
BPTF-associated chromatin complex component 1 (BACC1) is a protein
from Homo sapiens identified by UniProt accession
Q8IXM2, 172 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | BPTF-associated chromatin complex component 1 |
|---|
| UniProt accession | Q8IXM2 |
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| Gene | BACC1 |
|---|
| Organism | Homo sapiens |
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| Length | 172 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- body height · score 0.19
- lymphocyte count · score 0.10
- mean platelet volume · score 0.10
- lymphocyte percentage of leukocytes · score 0.09
- neutrophil percentage of leukocytes · score 0.08
- oral squamous cell carcinoma · score 0.07
- triple-negative breast cancer · score 0.07
- neoplasm · score 0.06
- total blood protein measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IXM2-F1 | alphafold | PREDICTED | 69.55 | — |
Amino-acid sequence (172 residues)
MTSASTKVGE IFSAAGAAFT KLGELTMQLH PVADSSPAGA KWTETEIEML RAAVKRFGDD LNHISCVIKE RTVAQIKATV KRKVYEDSGI PLPAESPKKG PKKVASGVLS PPPAAPPPSS SSVPEAGGPP IKKQKADVTL SALNDSDANS DVVDIEGLGE TPPAKKLNFD QA
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