Large ribosomal subunit protein mL41 (MRPL41)

About Large ribosomal subunit protein mL41

Large ribosomal subunit protein mL41 (MRPL41) is a protein from Homo sapiens identified by UniProt accession Q8IXM3, 137 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL41
UniProt accession	Q8IXM3
Gene	MRPL41
Organism	Homo sapiens
Length	137 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
lysosomal storage disease · score 0.29
ovarian carcinoma · score 0.02
drug use measurement · score 0.02
cancer · score 0.02
Alzheimer disease · score 0.01
neoplasm · score 0.01
Crohn's disease · score 0.01
polycystic ovary syndrome · score 0.01
melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXM3-F1	alphafold	PREDICTED	90.92	—

Amino-acid sequence (137 residues)

MGVLAAAARC LVRGADRMSK WTSKRGPRSF RGRKGRGAKG IGFLTSGWRF VQIKEMVPEF VVPDLTGFKL KPYVSYLAPE SEETPLTAAQ LFSEAVAPAI EKDFKDGTFD PDNLEKYGFE PTQEGKLFQL YPRNFLR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards