Ciliary microtubule associated protein 1C (CIMAP1C)

About Ciliary microtubule associated protein 1C

Ciliary microtubule associated protein 1C (CIMAP1C) is a protein from Homo sapiens identified by UniProt accession Q8IXM7, 274 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Ciliary microtubule associated protein 1C
UniProt accession	Q8IXM7
Gene	CIMAP1C
Organism	Homo sapiens
Length	274 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

intraocular pressure measurement · score 0.12
hemoglobin measurement · score 0.05
psoriasis · score 0.02
papillary thyroid carcinoma · score 0.01
Crohn's disease · score 0.01
rosacea · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXM7-F1	alphafold	PREDICTED	70.10	—

Amino-acid sequence (274 residues)

MKLPKGTRSS VYFAQHPEKE PLPSRQEVKQ TPVIMAKIKG PGPAKYLRPS CTGYIDHDIS MFKAPAYTLH SRHSEKRMVC HSSPGPCYLL DPKITRFGMS SCPQVPMEER ISNLRLNPTL ASCQYYFEKI HPPGERRAPQ YTFGYRRPYR VMDLNPAPNQ YQMPLLLGPN TPVSRAAPCY SLASRDKNWF YKEDVAGGPG PTTYARPEPS IYQNRSPTYS MAKRFAYPLD LTPRPGPGSH EVQQVTVHKP HIPAFTMGIK HSLHLCPLVI DIRD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards