About Uncharacterized protein C12orf56
Uncharacterized protein C12orf56 (C12orf56) is a protein
from Homo sapiens identified by UniProt accession
Q8IXR9, 622 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Uncharacterized protein C12orf56 |
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| UniProt accession | Q8IXR9 |
|---|
| Gene | C12orf56 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 622 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.28
- platelet crit · score 0.25
- BMI-adjusted waist circumference · score 0.24
- mean corpuscular hemoglobin · score 0.24
- body height · score 0.12
- hemoglobin measurement · score 0.12
- reticulocyte measurement · score 0.11
- hematocrit · score 0.11
- mean corpuscular hemoglobin concentration · score 0.10
- Female infertility due to fertilization defect · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IXR9-F1 | alphafold | PREDICTED | 70.61 | — |
Amino-acid sequence (622 residues)
MASPLPSGFP ARRNSRLDVF LRRHLPPEVY DAVRAYEPCI VVSNSENHIL KYVVLSDRLV YLTENPPKSI RRVVALRDVV AIDLIDDYPE FLSSPDREIS QHIRIIYSST VLKKECKKSN SVRKFLFPFH HTKANNKKVK EEKNGLAFWR SKESRSLKES PLRDQQESST PSKDSTLCPR PGLKKLSLHG QGAFRPLPSP SRRSSQSAPT TGKAVSEPSC TTNTKEPQGL PDHNSISEIP FKCNGNGNEF YLGNSLLDSP SQSNSNLEKK ESELHLYVIS TTSSIFLHLK SSWNNYIIKA TLLQDPFYAS EFSPAIGSQK PYRSEEKIKH FSQLKSELFL KDNSLRRILS LLMELKVAAQ KNFILKRLFW KTSDLFYFIV NKLHEYLPES RDKNALQNQS QRVDELVACI EIIQTLVLMF RETETESSRL NTLAAKKGAL FNLLVILISE PQIPKSCPVF DIQLVADSAL VRMSFDAELQ KLILEYTNTA TALLYEILLV FQQGNLGLGS TKFAISWIMS FLQSCPPIIT FVASIVKQVV RGLSASFQLL SPCQAVLLYQ QFYILKSCLR HSRTLAEYIR NNYREEFRYF IHMPALQKRL PLCYPITQPT IQLFHEVLKL VE
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