Hyccin 2 (HYCC2)

About Hyccin 2

Hyccin 2 (HYCC2) is a protein from Homo sapiens identified by UniProt accession Q8IXS8, 530 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Hyccin 2
UniProt accession	Q8IXS8
Gene	HYCC2
Organism	Homo sapiens
Length	530 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

chronic lymphocytic leukemia · score 0.25
body height · score 0.12
total blood protein measurement · score 0.09
monocyte count · score 0.06
rheumatoid arthritis · score 0.04
serum alanine aminotransferase measurement · score 0.03
mean corpuscular volume · score 0.03
mean platelet volume · score 0.03
mean reticulocyte volume · score 0.03
red blood cell density measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXS8-F1	alphafold	PREDICTED	67.99	—

Amino-acid sequence (530 residues)

MLGTDRCVVE EWLSEFKALP DTQITSYAAT LHRKKTLVPA LYKVIQDSNN ELLEPVCHQL FELYRSSEVR LKRFTLQFLP ELMWVYLRLT VSRDRQSNGC IEALLLGIYN LEIADKDGNN KVLSFTIPSL SKPSIYHEPS TIGSMALTEG ALCQHDLIRV VYSDLHPQRE TFTAQNRFEV LSFLMLCYNS AIVYMPASSY QSLCRMGSRV CVSGFPRQHE KHWKELCGRI VLDPEFMVQL LTGVYYAMYN GQWDLGQEVL DDIIYRAQLE LFSQPLLVAN AMKNSLPFDA PDSTQEGQKV LKVEVTPTVP RISRTAITTA SIRRHRWRRE GAEGVNGGEE SVNLNDADEG FSSGASLSSQ PIGTKPSSSS QRGSLRKVAT GRSAKDKETA SAIKSSESPR DSVVRKQYVQ QPTDLSVDSV ELTPMKKHLS LPAGQVVPKI NSLSLIRTAS ASSSKSFDYV NGSQASTSIG VGTEGGTNLA ANNANRYSTV SLQEDRLGQA GEGKELLSPG APLTKQSRSP SFNMQLISQV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards