Doublesex- and mab-3-related transcription factor C2 (DMRTC2)

About Doublesex- and mab-3-related transcription factor C2

Doublesex- and mab-3-related transcription factor C2 (DMRTC2) is a protein from Homo sapiens identified by UniProt accession Q8IXT2, 367 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein name	Doublesex- and mab-3-related transcription factor C2
UniProt accession	Q8IXT2
Gene	DMRTC2
Organism	Homo sapiens
Length	367 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IXT2-F1	alphafold	PREDICTED	59.96	—

Amino-acid sequence (367 residues)

MEPSDMPAGY HCPLDSAPWD ETRDPQSTEL IPRRAISRSP TCARCRNHGV TAHLKGHKRL CLFQACECHK CVLILERRRV MAAQVALRRQ QEAQLKKHLM RRGEASPKAP NHFRKGTTQP QVPSGKENIA PQPQTPHGAV LLAPTPPGKN SCGPLLLSHP PEASPLSWTP VPPGPWVPGH WLPPGFSMPP PVVCRLLYQE PAVSLPPFPG FDPGTSLQLP THGPFTTCPG SHPVLTAPLS GEPQGPPSQP RTHSTLILQP CGTPDPLQLQ PQASGASCLA RTSGPSEWQL QQEAAEALVG LKDSSQAPRV TPSVPPNPAW ISLLHPCGPP APAGGRGFQP VGPCLRPSPA PSVALHIGRL GSISLLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards