About Lamin tail domain-containing protein 2
Lamin tail domain-containing protein 2 (LMNTD2) is a protein
from Homo sapiens identified by UniProt accession
Q8IXW0, 634 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Lamin tail domain-containing protein 2 |
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| UniProt accession | Q8IXW0 |
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| Gene | LMNTD2 |
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| Organism | Homo sapiens |
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| Length | 634 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IXW0-F1 | alphafold | PREDICTED | 54.77 | — |
Amino-acid sequence (634 residues)
MRWLRPAGRR REQESVSGHL GPPAGAPAAP ETPTCLPDTT PHPAPVVCSA DPQLALESLD PRTLRLLWRQ RELEIQALRW AIQNGEDARL CHILEEVAGL PPKRSSHSQE KLLQNQVQKL IQELKEQKER AQWEKEHLEE RLLQTTRTLQ EMEAELQNLQ KSCLLQLARS SWVGRMLRSQ TGSVEVVTAE TLMDPSDLSE NIQAPTGEGF RLEDVDWNSV ARRYPNLFTN MEPSSKQKQP RPWPQLDTGS PESSGKHSER HHKTVEWGSL PCLNTSSSGG ADSDSSSCRP GLPSFVQVIG HPPRDHRASS EQALVQAGSY SRDSEDLQKT HSPRHGEPVL SPQPCTDPDH WSPELLQSPT GLKIVAVSCR EKFVRIFNPS QESTADLSGM VLKQLVRGFP ERLYRFPPGT LLAPRHHVTV WGEATRSAKK PLRASSSREP VPLLSIRGCA TLLLSPKGEV LSEHRIPRRE TPAPRVFADG TDLSIDRFPL PEAGPGADTR KPPRPPRPLR KGRVREPRVS RRRPGTRGLL PPVSSGKLFH AREGPARPEN PEIPAPQHLP AIPGDPTLPS PPAEAGLGLE DCRLQKEHRV RVCRKSVDRS CPLVALSVQN TAESRFGFRF LSCLPVTADT CRGA
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