About Protein AMN1 homolog
Protein AMN1 homolog (AMN1) is a protein
from Homo sapiens identified by UniProt accession
Q8IY45, 258 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Protein AMN1 homolog |
|---|
| UniProt accession | Q8IY45 |
|---|
| Gene | AMN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- insulin like growth factor measurement · score 0.05
- C-reactive protein measurement · score 0.03
- IGF-1 measurement · score 0.02
- glioblastoma multiforme · score 0.01
- cancer · score 0.01
- chronic obstructive pulmonary disease · score 0.01
- ependymoma · score 0.00
- Alzheimer disease · score 0.00
- astrocytoma · score 0.00
- Pick disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IY45-F1 | alphafold | PREDICTED | 91.22 | — |
Amino-acid sequence (258 residues)
MPRPRRVSQL LDLCLWCFMK NISRYLTDIK PLPPNIKDRL IKIMSMQGQI TDSNISEILH PEVQTLDLRS CDISDAALLH LSNCRKLKKL NLNASKGNRV SVTSEGIKAV ASSCSYLHEA SLKRCCNLTD EGVVALALNC QLLKIIDLGG CLSITDVSLH ALGKNCPFLQ CVDFSATQVS DSGVIALVSG PCAKKLEEIH MGHCVNLTDG AVEAVLTYCP QIRILLFHGC PLITDHSREV LEQLVGPNKL KQVTWTVY
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