Interactor of HORMAD1 protein 1 (IHO1)

Homo sapiens — UniProt Q8IYA8

Gene: IHO1Homo sapiensSwissProt reviewed

About Interactor of HORMAD1 protein 1

Interactor of HORMAD1 protein 1 (IHO1) is a protein from Homo sapiens identified by UniProt accession Q8IYA8, 594 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein nameInteractor of HORMAD1 protein 1
UniProt accessionQ8IYA8
GeneIHO1
OrganismHomo sapiens
Length594 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8IYA8-F1alphafoldPREDICTED54.66—

Amino-acid sequence (594 residues)

MNFNVWNIKE MLSIPSGSGN KKSSNWNNNQ NDYSSLSDSQ FLFGSQFCPE NSETLSAPLD FGAHLRHSKQ SQQNYLEGEP SIFTKYQTKP QLFGGDIKDG GLFPPPLSVG KSKGLLEQFE EKKKRAKDKC DSETLYNFVS NVRESILRLQ TSVEKSEDHL SSRSQSILDS LETVAKTLQE TIQAQNDLVF EAVQDKGNME QAILEMKKRF EARQGEFIEM KSNLKHLEVL VAQQSQEFQQ LCEQLGQLNV PSVLAELKRL ISVPPVKDSA SQTSPPLAQS LNLTRQEKYT SEKPVLWQAQ ALPAAWNPGM GSLQPGEFDV WGEGAKNDDL QEEAALPAFG SHERNRHVKD KVVQTNCKNW AVTKTGAKNH GSSVPGHKIP SDRDLVSQGA SQLTSLEINF STSIKNACQK YQAQSMFLCD PREHLVIKQK DGTVEMRGKD KKQQPRKAHR AHRGRLIASK QKQIPIQTCK FNSKYQSPQP AISVPQSPFL GQQEPRAQPL HLQCPRSPRK PVCPILGGTV MPNKTVRAVQ GRLLQLSRCS SQDNWLLSSS SQGDHQMSWF SDLNLGCSET PLCKEAGKNL LYDLGFDSSD DDGF

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Quick facts

UniProtQ8IYA8
GeneIHO1
OrganismHomo sapiens
Length594
Binders0
Diseases103
View on UniProt