Transcription elongation factor A protein-like 8…

About Transcription elongation factor A protein-like 8

Transcription elongation factor A protein-like 8 (TCEAL8) is a protein from Homo sapiens identified by UniProt accession Q8IYN2, 117 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Transcription elongation factor A protein-like 8
UniProt accession	Q8IYN2
Gene	TCEAL8
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

cancer · score 0.06
juvenile dermatomyositis · score 0.01
chronic kidney disease · score 0.01
neoplasm · score 0.01
Duchenne muscular dystrophy · score 0.01
invasive breast ductal carcinoma · score 0.00
Alzheimer disease · score 0.00
hepatitis C virus induced hepatocellular carcinoma · score 0.00
Glucose intolerance · score 0.00
non-alcoholic fatty liver disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IYN2-F1	alphafold	PREDICTED	65.44	—

Amino-acid sequence (117 residues)

MQKSCEENEG KPQNMPKAEE DRPLEDVPQE AEGNPQPSEE GVSQEAEGNP RGGPNQPGQG FKEDTPVRHL DPEEMIRGVD ELERLREEIR RVRNKFVMMH WKQRHSRSRP YPVCFRP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Transcription elongation factor A protein-like 8 (TCEAL8)