UBA-like domain-containing protein 2 (UBALD2)

Homo sapiens — UniProt Q8IYN6

Gene: UBALD2Homo sapiensSwissProt reviewed

About UBA-like domain-containing protein 2

UBA-like domain-containing protein 2 (UBALD2) is a protein from Homo sapiens identified by UniProt accession Q8IYN6, 164 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein nameUBA-like domain-containing protein 2
UniProt accessionQ8IYN6
GeneUBALD2
OrganismHomo sapiens
Length164 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (13)

Diseases linked to this target (Open Targets).

  • triglyceride measurement · score 0.22
  • urate measurement · score 0.22
  • BMI-adjusted waist-hip ratio · score 0.10
  • high density lipoprotein cholesterol measurement · score 0.09
  • neutrophil count · score 0.08
  • waist-hip ratio · score 0.06
  • monocyte percentage of leukocytes · score 0.05
  • reticulocyte count · score 0.03
  • inflammation · score 0.00
  • acute myeloid leukemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8IYN6-F1alphafoldPREDICTED63.93—

Amino-acid sequence (164 residues)

MSVNMDELRH QVMINQFVLA AGCAADQAKQ LLQAAHWQFE TALSTFFQET NIPNSHHHHQ MMCTPSNTPA TPPNFPDALA MFSKLRASEG LQSSNSPMTA AACSPPANFS PFWASSPPSH QAPWIPPSSP TTFHHLHRPQ PTWPPGAQQG GAQQKAMAAM DGQR

Explore UBA-like domain-containing protein 2 with MolForge

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Quick facts

UniProtQ8IYN6
GeneUBALD2
OrganismHomo sapiens
Length164
Binders0
Diseases13
View on UniProt