Serine protease 58 (PRSS58)

About Serine protease 58

Serine protease 58 (PRSS58) is a protein from Homo sapiens identified by UniProt accession Q8IYP2, 241 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Serine protease 58
UniProt accession	Q8IYP2
Gene	PRSS58
Organism	Homo sapiens
Length	241 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

Leigh syndrome · score 0.00
Crohn's disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IYP2-F1	alphafold	PREDICTED	90.35	—

Amino-acid sequence (241 residues)

MKFILLWALL NLTVALAFNP DYTVSSTPPY LVYLKSDYLP CAGVLIHPLW VITAAHCNLP KLRVILGVTI PADSNEKHLQ VIGYEKMIHH PHFSVTSIDH DIMLIKLKTE AELNDYVKLA NLPYQTISEN TMCSVSTWSY NVCDIYKEPD SLQTVNISVI SKPQCRDAYK TYNITENMLC VGIVPGRRQP CKEVSAAPAI CNGMLQGILS FADGCVLRAD VGIYAKIFYY IPWIENVIQN N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards