About Uncharacterized protein KIAA2013
Uncharacterized protein KIAA2013 (KIAA2013) is a protein
from Homo sapiens identified by UniProt accession
Q8IYS2, 634 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Uncharacterized protein KIAA2013 |
|---|
| UniProt accession | Q8IYS2 |
|---|
| Gene | KIAA2013 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 634 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.22
- alcohol drinking · score 0.21
- mean arterial pressure · score 0.17
- red blood cell folate measurement · score 0.16
- homocysteine measurement · score 0.16
- systolic blood pressure · score 0.15
- folic acid measurement · score 0.13
- blood protein measurement · score 0.13
- sum of eosinophil and basophil counts · score 0.06
- lymphocyte percentage of leukocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IYS2-F1 | alphafold | PREDICTED | 84.89 | — |
Amino-acid sequence (634 residues)
MWLQQRLKGL PGLLSSSWAR RLLCLLGLLL LLLWFGGSGA RRAAGGLHLL PWSRGEPGAA EPSACLEAAT RAWRGLRERG EVVPLGPGVP ALVANGFLAL DVAANRLWVT PGEREPAVAP DFVPFVQLRP LSALAEAGEA VLLLREGLLR RVRCLQLGSP GPGPVAAGPG PASVSGLAAG SGRDCVLLQE DFLAHRGRPH VYLQRIQLNN PTERVAALQT VGPTAGPAPK AFTSTLEKVG DHQFLLYSGR SPPTPTGLVH LVVVAAKKLV NRLQVAPKTQ LDETVLWVVH VSGPINPQVL KSKAAKELKA LQDLARKEML ELLDMPAAEL LQDHQLLWAQ LFSPGVEMKK ITDTHTPSGL TVNLTLYYML SCSPAPLLSP SLSHRERDQM ESTLNYEDHC FSGHATMHAE NLWPGRLSSV QQILQLSDLW RLTLQKRGCK GLVKVGAPGI LQGMVLSFGG LQFTENHLQF QADPDVLHNS YALHGIRYKN DHINLAVLAD AEGKPYLHVS VESRGQPVKI YACKAGCLDE PVELTSAPTG HTFSVMVTQP ITPLLYISTD LTHLQDLRHT LHLKAILAHD EHMAQQDPGL PFLFWFSVAS LITLFHLFLF KLIYNEYCGP GAKPLFRSKE DPSV
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