Leucine-rich repeat-containing protein 34 (LRRC34)

About Leucine-rich repeat-containing protein 34

Leucine-rich repeat-containing protein 34 (LRRC34) is a protein from Homo sapiens identified by UniProt accession Q8IZ02, 464 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Leucine-rich repeat-containing protein 34
UniProt accession	Q8IZ02
Gene	LRRC34
Organism	Homo sapiens
Length	464 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IZ02-F1	alphafold	PREDICTED	85.87	—

Amino-acid sequence (464 residues)

MAAQPPRPVG ERSMGSSREA ARAPARSPAW ASTQASTPGA ALAVQRESPE SGLQKHYSNL CMEKSQKINP FILHILQEVD EEIKKGLAAG ITLNIAGNNR LVPVERVTGE DFWILSKILK NCLYINGLDV GYNLLCDVGA YYAAKLLQKQ LNLIYLNLMF NDIGPEGGEL IAKVLHKNRT LKYLRMTGNK IENKGGMFFA AMLQINSSLE KLDLGDCDLG MQSVIAFATV LTQNQAIKAI NLNRPILYSE QEESTVHVGR MLKENHCLVA LHMCKHDIKN SGIQQLCDAL YLNSSLRYLD VSCNKITHDG MVYLADVLKS NTTLEVIDLS FNRIENAGAN YLSETLTSHN RSLKALSVVS NNIEGEGLVA LSQSMKTNLT FSHIYIWGNK FDEATCIAYS DLIQMGCLKP DNTDVEPFVV DGRVYLAEVS NGLKKHYYWT STYGESYDHS SNAGFALVPV GQQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards