About Neurensin-1
Neurensin-1 (NRSN1) is a protein
from Homo sapiens identified by UniProt accession
Q8IZ57, 195 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Neurensin-1 |
|---|
| UniProt accession | Q8IZ57 |
|---|
| Gene | NRSN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 195 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.35
- creatinine measurement · score 0.26
- diffuse plaque measurement · score 0.20
- connective tissue disease · score 0.14
- adolescent idiopathic scoliosis · score 0.13
- body mass index · score 0.06
- intelligence · score 0.05
- blood urea nitrogen measurement · score 0.05
- serum urea measurement · score 0.04
- Hirschsprung disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZ57-F1 | alphafold | PREDICTED | 69.42 | — |
Amino-acid sequence (195 residues)
MSSCSNVCGS RQAQAAAEGG YQRYGVRSYL HQFYEDCTAS IWEYEDDFQI QRSPNRWSSV FWKVGLISGT VFVILGLTVL AVGFLVPPKI EAFGEADFVV VDTHAVQFNS ALDMYKLAGA VLFCIGGTSM AGCLLMSVFV KSYSKEEKFL QQKFKERIAD IKAHTQPVTK APGPGETKIP VTLSRVQNVQ PLLAT
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