About ELMO domain-containing protein 2
ELMO domain-containing protein 2 (ELMOD2) is a protein
from Homo sapiens identified by UniProt accession
Q8IZ81, 293 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | ELMO domain-containing protein 2 |
|---|
| UniProt accession | Q8IZ81 |
|---|
| Gene | ELMOD2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 293 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.04
- hemoglobin D disease · score 0.04
- cholesterol-ester transfer protein deficiency · score 0.03
- hypertriglyceridemia 2 · score 0.03
- Combined hyperlipidemia · score 0.03
- hemoglobin E-beta-thalassemia syndrome · score 0.03
- hemoglobin E disease · score 0.03
- PHF-tau measurement · score 0.02
- prostate carcinoma · score 0.02
- idiopathic pulmonary fibrosis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZ81-F1 | alphafold | PREDICTED | 94.64 | — |
Amino-acid sequence (293 residues)
MFISLWEFFY GHFFRFWMKW LLRQMTGKCE LQRIFDTYVG AQRTHRIENS LTYSKNKVLQ KATHVVQSEV DKYVDDIMKE KNINPEKDAS FKICMKMCLL QITGYKQLYL DVESVRKRPY DSDNLQHEEL LMKLWNLLMP TKKLNARISK QWAEIGFQGD DPKTDFRGMG ILGLINLVYF SENYTSEAHQ ILSRSNHPKL GYSYAIVGIN LTEMAYSLLK SEALKFHLYN LVPGIPTMEH FHQFYCYLVY EFDKFWFEEE PESIMYFNLY REKFHEKIKG LLLDCNVALT LKV
Explore ELMO domain-containing protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets