About Zinc finger protein 101
Zinc finger protein 101 (ZNF101) is a protein
from Homo sapiens identified by UniProt accession
Q8IZC7, 436 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Zinc finger protein 101 |
|---|
| UniProt accession | Q8IZC7 |
|---|
| Gene | ZNF101 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 436 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- neutrophil count · score 0.34
- systolic blood pressure · score 0.29
- myeloid white cell count · score 0.25
- mean corpuscular hemoglobin concentration · score 0.25
- serum metabolite measurement · score 0.25
- lymphocyte percentage of leukocytes · score 0.18
- total cholesterol measurement · score 0.17
- neutrophil percentage of leukocytes · score 0.17
- triglyceride measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZC7-F1 | alphafold | PREDICTED | 66.27 | — |
Amino-acid sequence (436 residues)
MDSVAFEDVA VNFTQEEWAL LSPSQKNLYR DVTLETFRNL ASVGIQWKDQ DIENLYQNLG IKLRSLVERL CGRKEGNEHR ETFSQIPDCH LNKKSQTGVK PCKCSVCGKV FLRHSFLDRH MRAHAGHKRS ECGGEWRETP RKQKQHGKAS ISPSSGARRT VTPTRKRPYE CKVCGKAFNS PNLFQIHQRT HTGKRSYKCR EIVRAFTVSS FFRKHGKMHT GEKRYECKYC GKPIDYPSLF QIHVRTHTGE KPYKCKQCGK AFISAGYLRT HEIRSHALEK SHQCQECGKK LSCSSSLHRH ERTHSGGKLY ECQKCAKVFR CPTSLQAHER AHTGERPYEC NKCGKTFNYP SCFRRHKKTH SGEKPYECTR CGKAFGWCSS LRRHEMTHTG EKPFDCKQCG KVFTFSNYLR LHERTHLAGR SQCFGRRQGD HLSPGV
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