About Adhesion G-protein coupled receptor F3
Adhesion G-protein coupled receptor F3 (ADGRF3) is a protein
from Homo sapiens identified by UniProt accession
Q8IZF5, 1079 residues long.
MolForge cross-references it against 0 known binders and
2 disease associations.
Target properties
| Protein name | Adhesion G-protein coupled receptor F3 |
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| UniProt accession | Q8IZF5 |
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| Gene | ADGRF3 |
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| Organism | Homo sapiens |
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| Length | 1079 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (2)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.06
- primitive neuroectodermal tumor · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZF5-F1 | alphafold | PREDICTED | 73.66 | — |
Amino-acid sequence (1079 residues)
MVCSAAPLLL LATTLPLLGS PVAQASQPVS ETGVRPREGL QRRQWGPLIG RDKAWNERID RPFPACPIPL SSSFGRWPKG QTMWAQTSTL TLTEEELGQS QAGGESGSGQ LLDQENGAGE SALVSVYVHL DFPDKTWPPE LSRTLTLPAA SASSSPRPLL TGLRLTTECN VNHKGNFYCA CLSGYQWNTS ICLHYPPCQS LHNHQPCGCL VFSHPEPGYC QLLPPGSPVT CLPAVPGILN LNSQLQMPGD TLSLTLHLSQ EATNLSWFLR HPGSPSPILL QPGTQVSVTS SHGQAALSVS NMSHHWAGEY MSCFEAQGFK WNLYEVVRVP LKATDVARLP YQLSISCATS PGFQLSCCIP STNLAYTAAW SPGEGSKASS FNESGSQCFV LAVQRCPMAD TTYACDLQSL GLAPLRVPIS ITIIQDGDIT CPEDASVLTW NVTKAGHVAQ APCPESKRGI VRRLCGADGV WGPVHSSCTD ARLLALFTRT KLLQAGQGSP AEEVPQILAQ LPGQAAEASS PSDLLTLLST MKYVAKVVAE ARIQLDRRAL KNLLIATDKV LDMDTRSLWT LAQARKPWAG STLLLAVETL ACSLCPQDHP FAFSLPNVLL QSQLFGPTFP ADYSISFPTR PPLQAQIPRH SLAPLVRNGT EISITSLVLR KLDHLLPSNY GQGLGDSLYA TPGLVLVISI MAGDRAFSQG EVIMDFGNTD GSPHCVFWDH SLFQGRGGWS KEGCQAQVAS ASPTAQCLCQ HLTAFSVLMS PHTVPEEPAL ALLTQVGLGA SILALLVCLG VYWLVWRVVV RNKISYFRHA ALLNMVFCLL AADTCFLGAP FLSPGPRSPL CLAAAFLCHF LYLATFFWML AQALVLAHQL LFVFHQLAKH RVLPLMVLLG YLCPLGLAGV TLGLYLPQGQ YLREGECWLD GKGGALYTFV GPVLAIIGVN GLVLAMAMLK LLRPSLSEGP PAEKRQALLG VIKALLILTP IFGLTWGLGL ATLLEEVSTV PHYIFTILNT LQGVFILLFG CLMDRKIQEA LRKRFCRAQA PSSTISLVSC CLQILSCASK SMSEGIPWPS SEDMGTARS
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