About RING finger protein 113B
RING finger protein 113B (RNF113B) is a protein
from Homo sapiens identified by UniProt accession
Q8IZP6, 322 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | RING finger protein 113B |
|---|
| UniProt accession | Q8IZP6 |
|---|
| Gene | RNF113B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 322 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.18
- PHF-tau measurement · score 0.11
- gut microbiome measurement · score 0.11
- bacterial pathogen genotype measurement · score 0.11
- pneumococcal meningitis · score 0.11
- mathematical ability · score 0.02
- peripheral arterial disease · score 0.02
- cystatin C measurement · score 0.02
- blood protein measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZP6-F1 | alphafold | PREDICTED | 71.76 | — |
Amino-acid sequence (322 residues)
MAAPPSPGRT ADQADQVCTF LFKKPGRKGA AGLRKRPACD PEHGESSSSG DEGDTVAQPP RVAPRPRGLH SWQKAAHGDR RGEEAAPESL DVVYRSTRSA KPVGPEDMGA TADFEQDTEK EHHTPTILKC SQRVQEALRG REHDHIYRGI HSYLRYLKPK DTSMGNSSSG MARKGPIRAP GHLRATVRWD YQPDICKDYK ETGFCGFGDS CKFLHDRSDY KLGWEIEREL EEGRYCICED ENHEVGSEEE EIPFRCFICR QAFQNPVVTK CRHYFCESCA LEHFRATPRC YICDQPTGGI FNPAKELMAK LQKLQAAEGK KR
Explore RING finger protein 113B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets