Protein APCDD1 (APCDD1)

About Protein APCDD1

Protein APCDD1 (APCDD1) is a protein from Homo sapiens identified by UniProt accession Q8J025, 514 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein name	Protein APCDD1
UniProt accession	Q8J025
Gene	APCDD1
Organism	Homo sapiens
Length	514 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (99)

Diseases linked to this target (Open Targets).

hypotrichosis simplex · score 0.59
heel bone mineral density · score 0.43
age at menopause · score 0.42
cortical surface area measurement · score 0.41
hair shape measurement · score 0.39
balding measurement · score 0.37
neurodegenerative disease · score 0.34
alopecia · score 0.32
venous thromboembolism · score 0.29
bone quantitative ultrasound measurement · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8J025-F1	alphafold	PREDICTED	81.79	—

Amino-acid sequence (514 residues)

MSWPRRLLLR YLFPALLLHG LGEGSALLHP DSRSHPRSLE KSAWRAFKES QCHHMLKHLH NGARITVQMP PTIEGHWVST GCEVRSGPEF ITRSYRFYHN NTFKAYQFYY GSNRCTNPTY TLIIRGKIRL RQASWIIRGG TEADYQLHNV QVICHTEAVA EKLGQQVNRT CPGFLADGGP WVQDVAYDLW REENGCECTK AVNFAMHELQ LIRVEKQYLH HNLDHLVEEL FLGDIHTDAT QRMFYRPSSY QPPLQNAKNH DHACIACRII YRSDEHHPPI LPPKADLTIG LHGEWVSQRC EVRPEVLFLT RHFIFHDNNN TWEGHYYHYS DPVCKHPTFS IYARGRYSRG VLSSRVMGGT EFVFKVNHMK VTPMDAATAS LLNVFNGNEC GAEGSWQVGI QQDVTHTNGC VALGIKLPHT EYEIFKMEQD ARGRYLLFNG QRPSDGSSPD RPEKRATSYQ MPLVQCASSS PRAEDLAEDS GSSLYGRAPG RHTWSLLLAA LACLVPLLHW NIRR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards