Beta-defensin 106 (DEFB106A)

About Beta-defensin 106

Beta-defensin 106 (DEFB106A) is a protein from Homo sapiens identified by UniProt accession Q8N104, 65 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Beta-defensin 106
UniProt accession	Q8N104
Gene	DEFB106A
Organism	Homo sapiens
Length	65 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

Autosomal dominant striatal neurodegeneration · score 0.04
neuroticism measurement · score 0.04
emotional symptom measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N104-F1	alphafold	PREDICTED	82.32	—

Amino-acid sequence (65 residues)

MRTFLFLFAV LFFLTPAKNA FFDEKCNKLK GTCKNNCGKN EELIALCQKS LKCCRTIQPC GSIID

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards