Cytochrome P450 4X1 (CYP4X1)

About Cytochrome P450 4X1

Cytochrome P450 4X1 (CYP4X1) is a protein from Homo sapiens identified by UniProt accession Q8N118, 509 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Cytochrome P450 4X1
UniProt accession	Q8N118
Gene	CYP4X1
Organism	Homo sapiens
Length	509 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

astrocytoma · score 0.04
atypical teratoid rhabdoid tumor · score 0.04
central nervous system cancer · score 0.03
ependymoma · score 0.03
glioblastoma multiforme · score 0.03
Obesity · score 0.03
obesity · score 0.03
medulloblastoma · score 0.02
oligodendroglioma · score 0.02
large cell medulloblastoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N118-F1	alphafold	PREDICTED	89.07	—

Amino-acid sequence (509 residues)

MEFSWLETRW ARPFYLAFVF CLALGLLQAI KLYLRRQRLL RDLRPFPAPP THWFLGHQKF IQDDNMEKLE EIIEKYPRAF PFWIGPFQAF FCIYDPDYAK TLLSRTDPKS QYLQKFSPPL LGKGLAALDG PKWFQHRRLL TPGFHFNILK AYIEVMAHSV KMMLDKWEKI CSTQDTSVEV YEHINSMSLD IIMKCAFSKE TNCQTNSTHD PYAKAIFELS KIIFHRLYSL LYHSDIIFKL SPQGYRFQKL SRVLNQYTDT IIQERKKSLQ AGVKQDNTPK RKYQDFLDIV LSAKDESGSS FSDIDVHSEV STFLLAGHDT LAASISWILY CLALNPEHQE RCREEVRGIL GDGSSITWDQ LGEMSYTTMC IKETCRLIPA VPSISRDLSK PLTFPDGCTL PAGITVVLSI WGLHHNPAVW KNPKVFDPLR FSQENSDQRH PYAYLPFSAG SRNCIGQEFA MIELKVTIAL ILLHFRVTPD PTRPLTFPNH FILKPKNGMY LHLKKLSEC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards