About CPX chromosomal region candidate gene 1 protein
CPX chromosomal region candidate gene 1 protein (CPXCR1) is a protein
from Homo sapiens identified by UniProt accession
Q8N123, 301 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | CPX chromosomal region candidate gene 1 protein |
|---|
| UniProt accession | Q8N123 |
|---|
| Gene | CPXCR1 |
|---|
| Organism | Homo sapiens |
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| Length | 301 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- leukocyte count · score 0.05
- lymphocyte count · score 0.05
- calf circumference measurement · score 0.03
- schizophrenia · score 0.01
- cleft palate with or without ankyloglossia, X-linked · score 0.01
- Abnormal sperm morphology · score 0.01
- cancer · score 0.01
- Obesity · score 0.00
- cleft palate · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N123-F1 | alphafold | PREDICTED | 50.02 | — |
Amino-acid sequence (301 residues)
MSYPTKEGSD TAGNAHKNSE NEPPNDCSTD IESPSADPNM IYQVETNPIN REPGTATSQE DVVPQAAENS ELETEIQKDQ REEDLKEELL LLQTPIPRKL VSHKPLNDRS RSHSGKVEMK ANNFPINHKT RFRLSTSWRV PFINSHEIRS MILHLLCDRY FSQAAGCQNT MWVKRKYIAC LYHPNSFTHH ERAITFRRPS RVHYYRPLTE RMTSGKFCKS TDTKGKCRFR AIVRSVLFVS QIQIESIFNI KGFVDILTYI HTMNVMITNT NNGWKYFCPI CGRLFNTYSE LRQHSCSSSG N
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