Olfactory receptor 5AS1 (OR5AS1)

About Olfactory receptor 5AS1

Olfactory receptor 5AS1 (OR5AS1) is a protein from Homo sapiens identified by UniProt accession Q8N127, 324 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Olfactory receptor 5AS1
UniProt accession	Q8N127
Gene	OR5AS1
Organism	Homo sapiens
Length	324 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.30
thyroid gland adenocarcinoma · score 0.22
hepatocellular carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
ovarian cancer · score 0.18
low grade glioma · score 0.18
breast adenocarcinoma · score 0.18
acute myeloid leukemia · score 0.14
myeloid white cell count · score 0.12
cystatin C measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N127-F1	alphafold	PREDICTED	88.19	—

Amino-acid sequence (324 residues)

MLESNYTMPT EFLFVGFTDY LPLRVTLFLV FLLVYTLTMV GNILLIILVN INSSLQIPMY YFLSNLSFLD ISCSTAITPK MLANFLASRK SISPYGCALQ MFFFASFADA ECLILAAMAY DRYAAICNPL LYTTLMSRRV CVCFIVLAYF SGSTTSLVHV CLTFRLSFCG SNIVNHFFCD IPPLLALSCT DTQINQLLLF ALCSFIQTST FVVIFISYFC ILITVLSIKS SGGRSKTFST CASHLIAVTL FYGALLFMYL QPTTSYSLDT DKVVAVFYTV VFPMFNPIIY SFRNKDVKNA LKKLLERIGY SNEWYLNRLR IVNI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards